DDX27 expression in primary colon cancer was an independent prognostic marker for survival in both Beijing cohort (P < 0.05; hazard ratio: 3.362; 95% CI, 1.157 to 9.771; Table S7 and S8) and TCGA cohort (P < 0.05; hazard ratio: 7.345; 95% CI, 1.014 to 53.203; Table S9 and S10). This evidence concerns the gene DDX27 and malignant colon neoplasm.