IDH2 and neoplasm: In particular, patients bearing only the SNP (mean age 55.7 years) were older that patients bearing both the SNP and IDH missense tumor mutations (mean 45.6ys, p < 0.05, Tukey’s multiple comparisons test), or those bearing only missense mutations (mean 42.3ys, p < 0.001, Tukey’s multiple comparisons test).