We additionally identified statistically significant mutations in the metalloproteinases ADAMTS2 (15%) and ADAMTS12 (20%), and in GAS7 (12%) and NTM (10%) (Q < 0.01, Methods section, Fig. 1a, Supplementary Fig. 4c, Supplementary Data 6–7), which so far have not been reported as significantly mutated in any other lung cancer subtype. The gene discussed is ADAMTS2; the disease is lung carcinoma.