STK11 and adenocarcinoma: Although, LCNECs also harbored alterations commonly observed in adenocarcinomas and squamous cell carcinomas, even LCNECs with such alterations in KEAP1 or STK11 were primarily found in transcriptional subclasses shared with SCLC (Fig. 2a, Supplementary Fig. 7c, Supplementary Data 12).