Lung neuroendocrine tumors, on the contrary, showed significantly higher expression of neuroendocrine and endocrine markers, Hu antigens (ELAVL3 and ELAVL4) and the lineage transcription factor and oncogene ASCL1, which is in agreement with previous studies on lung cancer subtypes11–13,18,29 (Q < 0.05, Methods section). Here, ASCL1 is linked to lung cancer.