Using an inducible shRNA expression system with KIFC1 shRNA doxycycline-induced KIFC1 depletion resulted in significant tumor growth inhibition in both cell lines (Fig. 4g) in contrast to non-targeting (NT) control cell xenografts (Supplementary Figure 7a) (two-way ANOVA with Sidak’s multiple comparisons test). This evidence concerns the gene KIFC1 and neoplasm.