The second-best phene “DIST CD68 TO CD34 IN nonIntact” which is also closely related to the 6th-ranked “RATIO #CD68_border2 TO #CD34_border1” as well includes the microvessel density in the tumor region, stating that larger distance of CD68(+) macrophages to microvessels or a high density of CD68(+) macrophages together with a low microvessel density point to a good prognosis. Here, CD34 is linked to neoplasm.