Clinical features, including blood in the stool, liver enlargement, ICU admission, number of days in ICU, low or high haematocrit, low or high WBC count, high creatinine, high urea, low platelet count, rapid pulse, rapid respiratory rate, low Glasgow Coma Score (GCS), pleural effusion (only one case), abdominal pain, urinary protein, urinary RBC, and high ALT, were considered on a case-by-case basis when clinicians classified dengue as severe or non-severe. This evidence concerns the gene GPT and dengue disease.