We demonstrated that a low preoperative PNI value was associated with age, BMI, white and red blood cell counts, a large tumor size, deep invasion, lymph node metastasis, an advanced pStage, lower albumin concentrations, and higher C-reactive protein levels, but not preoperative serum CEA levels. Here, CEACAM5 is linked to metastatic malignant neoplasm in the lymph nodes.