In a separate pooled analysis of 2226 subjects who were either healthy, or had dyslipidemia, MetS or T2DM, Blanco Mejia et al. (2014) [44] reported tree nut interventions of similar median duration and dose (49.3 g/day) were also effective in lowering fasting blood glucose (MD = −0.08 mmol/L (95% CI: −0.16, −0.01); p < 0.05) by an amount similar to that observed in our study (−0.08 mmol/L change in glucose), when compared with a control diet; however, insulin was not included in their analysis. This evidence concerns the gene INS and metabolic syndrome.