PROM1 and cryohydrocytosis: It has been shown that miR-122, miR-192, miR-125a-5p and miR-181b were significantly common up regulated miRNAs in CD133+ cells of the HCC group (fold change = 5, 6.7, 2.3 & 39.5, P value = 0.001025, 0.000024 & 0.0000001; respectively) up on comparing CD133+ cells of the malignant group (HCC group) to the other non-malignant groups (CHC, LC and control groups) as shown in S6 Table.