On comparing CD133+ cells of the HCC group to the LC group; miR-122, miR-192, miR-885-5p, miR-224, miR-125a-5p, miR-181b and miR-199a-3p were significantly up regulated (fold change = 5, 6.7, 2.3, 3, 2.5, 4.2 & 39.5 P value = 0.001025, 0.000024, 0.000472, 0.000278, 0.000004, 0.000075 & 0.0000001 respectively) whereas miR-22 was significantly down regulated (fold change = 0.57 P value = 0.00002) as shown in S5 Table and Fig 4B. Here, PROM1 is linked to hepatocellular carcinoma.