As for miR-122, miR-192 also enhances HCV replication [36]. Moreover, Yan-Chun et al., reported that miR-192-5p promotes the proliferation and metastasis of HCC expressing CD133 and CD90 cell surface markers through targeting semaphorin 3A (SEMA3A) [37]. This evidence concerns the gene PROM1 and hepatocellular carcinoma.