In fact, the genes nleA, nleB, nleC, nleE, nleF, nleG, nleG2-1, nleG2-3, nleG5-2, nleG6-2, nleG9, nleH1, nleH2 and ent/espL2 were more prevalent in isolates associated with HUS (SPT A–C) than in strains associated with only diarrhoea or animals (SPT DE) [37]. Here, AGXT is linked to hemolytic-uremic syndrome.