EGF and posterior cortical atrophy: Conclusively, we identified for the first time that anticancer Chinese traditional medicine CFF‐1 not only had the potential of specific anticancer effect, but could induce PCa cell growth inhibition, autophagy, and apoptosis in vitro and in vivo via targeting EGFR and competitively acting on EGFR with EGF and further suppressing the activity of EGFR/PI3K/AKT and EGFR/PI3K/Raf/Erk signal pathways.