Among LC patients, circulating median or mean concentrations of AFR, NLR, PLR, MLR, Fib, and Alb were 10.04 (4.54–34.39), 2.74 (0.10–13.36), 136.58 (10.56–1173.68), 0.28 (0.003–1.33), 3.81 ± 1.27 mg/dL, 39.17 (10.30–50.00) g/L, respectively, and significant differences in NLR, MLR, and Alb were observed in the three subgroups. This evidence concerns the gene ALB and laryngotracheoesophageal cleft.