Many transformed immune cells involved in chronic inflammation generated NSCLC‐related microenvironment, synthesized, and released numerous inflammatory factors such as fibroblast growth factor‐2 (FGF‐2), vascular endothelial growth factor (VEGF) and platelet‐derived growth factor (PDGF) 3, 6. This evidence concerns the gene FGF2 and non-small cell lung carcinoma.