For instance, plenty of intact and stable circRNAs were discovered within human serum exosomes, and therein the circ‐KLHDC10 expression showed evident distinctions between colorectal cancer patients and healthy individuals.12 In addition, ciRS‐7 (also termed as Cdr1as) not merely exhibited a higher expression within hepatocellular carcinoma (HCC) tissues than within para‐carcinoma tissues, but also was significantly correlated with hepatic microvascular invasion (MVI) among patients with NSCLC.13 Therefore, ciRS‐7 was speculated as potential biomarker for diagnosing HCC or NSCLC. The gene discussed is KLHDC10; the disease is non-small cell lung carcinoma.