Furthermore, it was miR‐7 that hindered the migration of lung cancer through inhibiting phosphatidylinositol‐3‐kinase (PI3K) and Toll‐like receptor 9 (TLR9) expressions.16 Based on the above‐mentioned researches, it could be summarized that ciRS‐7 combined with miR‐7 might modify proliferation, invasion and migration of cancer cells, although hardly any studies have associated ciRS‐7 with miR‐7 within NSCLC‐relevant investigations. This evidence concerns the gene TLR9 and lung cancer.