Of the remaining tubular carcinomas, 3 fell in IntClust 7 (with 16q loss and MAP3K1 mutations), 4 fell in IntClust 8 (1q gain, 16q loss and PIK3CA and GATA3 mutations) and 6 belonged to IntClust 4 (few copy number alterations and activation of immune pathways). Here, PIK3CA is linked to tubular adenocarcinoma.