EWSR1 and Ewing sarcoma: Reprogramming of the Ewing’s sarcoma cell line, CHLA-10, into iPS cells (EWS-iPS) showed that although the expression of EWS–FL1 fusion transcript between CHLA-10 and EWS-iPS is similar, EWS-iPS developed resistance to compounds targeting EWS–FL1 driven pathways84.