CYP2C19 and liver disorder: A wide variety of other medications including antiepileptic (phenytoin and carbamazepine), antidepressant (imipramine), antivirals (nelfinavir), and tuberculostatics (isoniazide and rifampin), extensively prescribed for patients with advanced liver diseases, are the substrate, inducer or inhibitor of CYP2C19 [36, 37].