However, recently, Molina et al. [28] have shown that CF airway epithelial cells (CuFi) display a lower TER, similar expression of TJ proteins (ZO-1 and ZO-2) on the plasma membrane and a Cx43 mistrafficking to the plasma membrane as compared with wild-type cells (NuLi), suggesting that a defect in gap junctions might influence TER. This evidence concerns the gene GJA1 and cystic fibrosis.