In addition to EP300, multiple 5′ fusion partners of ZNF384 have been reported in lymphoproliferative disorders including TAF15,9,10 ESWR1,9,10CREBBP,6 TCF3,6,9 ARID1B,9SYNRG3 and BMP2K,11 implying that ZNF384 is the predominant pathogenic lesion. The gene discussed is ZNF384; the disease is lymphoproliferative syndrome.