In our efforts to identify the genetic etiology for the clinical presentation for Lody, we sequenced the coding regions and flanking exon-intron boundaries of 10 ARVC-associated genes (LMNA, CTNNA3, DES, TGFB3, JUP, TMEM43, PKP2, DSC2, DSG2, and DSP) in our subject and compared his data to that of an unaffected female bonobo (Kitty). Here, DES is linked to arrhythmogenic right ventricular cardiomyopathy.