In ID8hPON2 cells, the expression profile of many genes known to regulate tumor growth including BRCA1, cyclin and cyclin-dependent kinase 20, PTK2, Hypoxia-upregulated protein 1, p21-activated kinase 3, IL-18, IL-33, IGF-1, IGFBP2 and RNA-binding protein 9, were identified. The gene discussed is IL18; the disease is neoplasm.