ESR1 and cancer: Including all nearest genes (regardless of whether they were also a CHi-C target gene) in our eQTL analysis we found two additional SNP-gene combinations that were not captured by our CHi-C analysis; rs4808801 was associated with levels of expression of ELL in all cancers and ER+ cancers and rs8170 was associated with levels of expression of ANKLE in all cancers (FDR adjusted t-test P < 0.1).