LASP1 and neoplasm: Cells transfected with sh-LASP1 had a significantly higher proportion of cells in the G1/G0 phase (P = 0.003) and a significantly lower proportion of cells in the G2/M phase (P = 0.031), which indicated that sh-LASP1 inhibited cell proliferation by arresting the tumor cells at the G1/G0 phase (Fig. 2c).