Further analysis by miRNA-mRNA interaction network showed that asi-miR-275 and asi-miR-305 contained predicted binding sites within the 3'UTR of PGRP-LB and APL1C, respectively, and the 3'-UTR of the anti-Plasmodium genes, such as PGRP-LC, PGRP-LD, Rel2, Caspar, IMD (immune deficiency pathway) and LRRD7/APL2, had in silico-predicted binding sites of many miRNAs. This evidence concerns the gene PGLYRP1 and Immunodeficiency.