In contrast, over-expression of lncRNA NONHSAT022487 followed by infection with T. gondii impaired the secretion of the cytokines IL-1β (t(4) = 2.721, P = 0.051) and IFN-γ (t(4) = 3.015, P = 0.041), and a more significant inhibition of secretion was observed in IL-12 (t(4) = 6.301, P = 0.0034) and TNF-α (t(4) = 6.625, P = 0.0028) in these cells (Fig. 7). This evidence concerns the gene TNF and infection.