They were located in 5 genes (RPS6KA1, ATF6B, HSD17B3, CREB3L1 and SRC), which fell under the estrogen signalling pathway (5 genes), the steroid hormone biosynthesis pathway, the GnRH signalling pathway, the progesterone-mediated oocyte maturation pathway, the prolactin signalling pathway, the oxytocin signalling pathway and the prostate cancer signalling pathway (one gene each). This evidence concerns the gene HSD17B3 and Familial prostate cancer.