As was the case with prostate cancer and HCC, these expression patterns were often dominated by particularly significant differences in expression of one or two RPTs, most commonly RPL3, RPS4X, RPL8, RPL30, and RPL13. Other tumor clusters, notably those involving the uterus, brain, and lung, possessed more complex differences involving larger numbers of RPTs (Figs. 2 and 3a). This evidence concerns the gene RPL8 and prostate cancer.