Interestingly, endothelial cells express Lewis antigen-binding proteins such as E-selectin (CD62E), P-selectin (CD62P), and the scavenger receptor C-type lectin (SRCL), supporting the idea that during cancer angiogenesis potential interactions between these receptors and their fucosylated ligands expressed by tumor cells exist (105). The gene discussed is COLEC12; the disease is cancer.