AKT1 and non-small cell lung carcinoma: Activation of PPARγ inhibits cell proliferation through up-regulation of expression of the tumor suppressor PTEN in human promyeloid leukemia cells (Lee et al., 2007), non-small-cell lung cancer (A549) cells (Lee et al., 2006), and PASMCs by inhibition of the PI3K/Akt pathway (Xie et al., 2015).