In a cross-sectional study carried out by All India Ophthalmological Society, prevalence of DR was 21.7% and the rate was high in males (p = 0.007), in patients with diabetes duration > 5 years (p = 0.001), in patients with age > 40 years (p = 0.01), in insulin users (p = 0.001), and in patients with history of vascular accidents (p = 0.0014) [2]. Here, INS is linked to diabetes mellitus.