The percentage of cells expressing PRA and PRB was increased 1.9- and 1.7-fold in E HRT and E+MPA luminal breast tumors, respectively (Figure 5), compared to no HRT normal postmenopausal breast (Figure 1), and were elevated compared to normal premenopausal breast levels (P < .05) (Figure 1). This evidence concerns the gene S100A6 and breast neoplasm.