ERBB2 and breast cancer: Similar to the effects of B49Mod1 on murine cell lines, a number of human non-tumorigenic (HMLE and MCF10a) and tumorigenic cell lines representing the 5 breast cancer subtypes (luminal A, luminal B, claudin low, basal, and HER2) with varying levels of BST-2 (low, medium, and high) mRNA (Fig. 7E) were analyzed for colony formation in the presence of B49Mod1 (Fig. 7F–H).