In the present study, we assessed whether intratumoural expression of DCTD or RRM1 may be prognostic for patients with pancreatic adenocarcinoma who had had post-operative adjuvant chemotherapy with either gemcitabine or 5-fluoruracil with folinic acid in the European Study Group for Pancreatic Cancer (ESPAC)-3(v2)-randomised adjuvant trial,4 and in patients from the combined ESPAC-1 and ESPAC-3(v1) post-operative pure observational groups.14 Here, DCTD is linked to familial pancreatic carcinoma.