Multivariate analysis revealed that ELF3 was an independent risk factor for HCC (OS: hazard ratio (HR) = 2.66, 95% confidence interval (95% CI): 1.28–5.55, p = 0.009; DFS: HR = 1.98, 95% CI: 1.13–3.47, p = 0.017) (Table 2). Here, ELF3 is linked to hepatocellular carcinoma.