In glioblastoma, patients with the lowest CD63 expression (score 0–6; n = 22) tended to have a significantly longer overall survival than the patients with the highest CD63 expression (score 9–12; n = 23) (HR 1.61; 95% CI 0.88–2.96; p = 0.12), and similar tendency was found when adjusting for age and sex (HR 1.72; 95% CI 0.91–3.25; p = 0.095). The gene discussed is CD63; the disease is glioblastoma.