Nlrp3, Asc, Caspase-1 KO mice and/or Nlrp3 Aim2 double KO mice were more susceptible to infection with A. fumigatus, C. albicans, C. neoformans, P. brasiliensis and S. schenckii [[63], [64], [65], [66], [67]]. Here, NLRP3 is linked to infection.