Furthermore, SSTR1 co-localized with active-caspase-3 and bcl-2 around the hematoma, while the expression of active-caspase-3 was parallel with that of SSTR1 in a time-dependent manner, indicating that up-regulated SSTR1 contributed to neuronal apoptosis following ICH [30]. This evidence concerns the gene SSTR1 and hematoma.