When comparing patients with histological diagnoses of NAFLD and NASH, NASH patients had higher mRNA expressions TGFB1 and LDLR expressions (respective up-regulations of 17 and 27%, both P < 0.05) and lower GNMT expression (down-regulated by 45%) (Table 3). The gene discussed is TGFB1; the disease is metabolic dysfunction-associated steatohepatitis.