NOD.MyD88LysM-KO, NOD.MyD88CD11c-KO, NOD.TRIFLysM-KO, NOD.TRIFCD11c-KO mice and their littermate controls carrying MyD88 or TRIF floxed alleles but not the respective Cre trangenes were monitored for diabetes development by weekly blood glucose measurements starting from the age of 8–10 weeks. The gene discussed is MYD88; the disease is diabetes mellitus.