ART4 and muscular dystrophy: Dystrophin is a component of the dystrophin-glycoprotein complex whose function is to provide stability to muscle membranes by bridging the cytoskeleton of the muscle to the extracellular matrix. Mutations in DMD cause Duchenne (DMD) and Becker (BMD) Muscular Dystrophies. Associations between variants in DMD and OFCs have been reported in four chromosome-wide analyses of X-linked SNPs.