GABRE encodes the “Gamma-aminobutyric acid type A receptor epsilon subunit.” This gene maps to a cluster on chromosome Xq28 that houses other subunits of the same receptor. Fatemi et al. (2013) reported increased expression of GABRE in the lateral cerebella of subjects with schizophrenia, bipolar disorder and major depressive disorder. This evidence concerns the gene GABRE and major depressive disorder.