Harper et al. (80) evaluated the expression of different IFN-α subtypes and their potency in HIV-1-exposed pDC using the lamina propria aggregate ex vivo culture model and reported that HIV infection induced numerous IFN-α subtypes with IFN-α6, IFN-α8, and IFN-α14 being the most potent at inhibiting HIV infection. The gene discussed is IFNA6; the disease is HIV infectious disease.