Beside the classification based on body localization, pemphigoid diseases may be classified based on targeted auto-antigens, such as 180 kDa BP antigen (BP180) and the 230 kDa BP antigen (BP230) in pemphigoid, laminin-332 in anti-laminin-332 MMP, the p200 protein in anti-p200 pemphigoid (anti-laminin γ1 pemphigoid), and type VII collagen in epidermolysis bullosa acquisita (EBA) (2). The gene discussed is COL17A1; the disease is autoimmune bullous skin disease.