After removing from the analysis the patients whose data overlapped with the previous study of our group (15), we found significant differences (P = 0.0002; Mann–Whitney test) in the expression level of BUB1B-PINK1 (Figure 5A) between patients whose final diagnosis was adenoma (median = 2.67; n = 34) and those whose final diagnosis was carcinoma (median = −0.176; n = 27). Here, BUB1B is linked to carcinoma.