EGR3 and schizophrenia: As a critical mediator of numerous biological processes disrupted in schizophrenia, such as growth factor signaling, myelination, vascularization, immune function, memory formation and synaptic plasticity (Gallitano-Mendel et al., 2007; Jones et al., 2007; Suehiro et al., 2010; Li et al., 2012; Kurosaka et al., 2017), insufficient activation of EGR3 may result in neuropathology that gives rise to schizophrenia.