EGR1 and schizophrenia: While a number of studies have identified associations between EGR1 and schizophrenia, the most significant is that of the 2014 Schizophrenia Working Group of the Psychiatric Genomics Consortium GWAS, in which EGR1 resides in region 69 of the 108 loci associated with the illness, and contains the Index SNP for that region (Schizophrenia Working Group of the Psychiatric Genomics Consortium, 2014).