Positive pairwise correlations of the biomarkers of inflammation were mainly observed for hsCRP, IL-6, IL-18 and IL-1RA with stronger associations in T2D (r between 0.33 and 0.61, all P < 0.001) than in T1D (r between 0.07 and 0.38, P between < 0.001 and 0.155) (Table 2). This evidence concerns the gene IL18 and type 1 diabetes mellitus.