YAP1 and central nervous system cancer: The biochemical analysis of mp53 gliomas, growing as CSCs, showed good correlation between high levels of WASP-interacting protein (WIP) and high levels of pAkt and pErk, and also between expression of the stem markers Yes-associated protein 1 (YAP) and Transcriptional co-activator with PDZ-binding motif (TAZ) [77].