The distribution of KRAS HS values (median 1.05, IQR 0.59–1.66) in our study corresponded closely to normal distribution of HS values according to the ‘one‐hit hypothesis’ for oncogenes, supporting the notions that KRAS mutations are usually clonally dominant truncal mutations and not associated with MASI in lung cancer (Chiosea et al., 2011; Uchiyama et al., 2003; Yu et al., 2017). Here, KRAS is linked to lung cancer.