In DRG neurons, 41.2% (7/17) of TRPM8 positive neurons expressed TLR5, 59.1% (13/22) of TRPV1 neurons expressed TLR5 and 44.4% (4/9) of TRPA1 neurons expressed TLR5 in the bleomycin-induced fibrosis model. This evidence concerns the gene TRPA1 and fibrosis.