In the bleomycin-induced fibrosis model, 16.6% (1/6) of TRPM8 positive neurons expressed TLR2, 31.5% (6/19) of TRPV1 neurons expressed TLR2, and 12.5% (1/8) of TRPA1 expressed TLR2 in nodose/jugular ganglion. This evidence concerns the gene TLR2 and fibrosis.