For many of these immunological readouts, we found significant interactions between mouse location and infection (S3 Table: At 3 weeks p.i., significant interaction terms for cytokines in LPMCs include IL-13, IL-4, and IL-17, and for MLN cells, IL-13, IFNγ, and IL-10), suggesting that the mice responded differently to nematode infection in the laboratory versus field. This evidence concerns the gene IFNG and infection.