A total of 70 transcripts showed a differential expression across iPSC differentiation among which 14 transcripts corresponded to genes associated with GWA study loci in BD including both ANK3 and CACNB3. Furthermore, BD risk genes regulated by miR-34a overexpression formed a highly connected protein interaction network indicating that miR-34a coordinately controls pathways relevant to neurodevelopment and the expression of multiple candidate BD risk genes. This evidence concerns the gene CACNB3 and Behcet disease.