Spinal DLBCL can be categorized into the germinal center B cell [CD10 (+) or CD10 (−)/BCL-6 (+)/MUM1 (−)] and nongerminal center B cell [CD10 (−)/BCL-6 (−) or CD10 (−)/BCL-6 (+)/MUM1 (−)] types. The gene discussed is MME; the disease is diffuse large B-cell lymphoma.